Boundary extension is attenuated in patients with ventromedial prefrontal cortex damage
نویسندگان
چکیده
منابع مشابه
Familial liability to psychosis is associated with attenuated dopamine stress signaling in ventromedial prefrontal cortex.
OBJECTIVE Patients diagnosed with a psychotic disorder and their first-degree relatives display increased reactivity to stress. Theory predicts that experience of psychosocial stress is associated both with ventromedial prefrontal and mesolimbic dopamine neurotransmission. However, while there is evidence of aberrant striatal dopamine processing in psychotic disorder, the role of the prefrontal...
متن کاملFocal ventromedial prefrontal cortex damage impairs convergence in discourse
Conversational partners tend to converge (become more similar) on various speech and discourse characteristics, enhancing social affiliation. We examined convergence in the discourse of eight participants with bilateral ventromedial prefrontal cortex (VMPC) damage and eight healthy comparison participants (NC) each interacting with a clinician. Changes in total words, words/turn, and backchanne...
متن کاملDamage to the ventromedial prefrontal cortex reduces interpersonal disgust.
Disgust for contaminating objects (core disgust), immoral behaviors (moral disgust) and unsavory others (interpersonal disgust), have been assumed to be closely related. It is not clear, however, whether different forms of disgust are mediated by overlapping or specific neural substrates. We report that 10 patients with damage to the ventromedial prefrontal cortex (vmPFC) avoided behaviors that...
متن کاملVentromedial Prefrontal Cortex Damage Is Associated with Decreased Ventral Striatum Volume and Response to Reward.
UNLABELLED The ventral striatum and ventromedial prefrontal cortex (vmPFC) are two central nodes of the "reward circuit" of the brain. Human neuroimaging studies have demonstrated coincident activation and functional connectivity between these brain regions, and animal studies have demonstrated that the vmPFC modulates ventral striatum activity. However, there have been no comparable data in hu...
متن کاملDamage to Ventromedial Prefrontal Cortex Impairs Judgment of Harmful Intent
Moral judgments, whether delivered in ordinary experience or in the courtroom, depend on our ability to infer intentions. We forgive unintentional or accidental harms and condemn failed attempts to harm. Prior work demonstrates that patients with damage to the ventromedial prefrontal cortex (VMPC) deliver abnormal judgments in response to moral dilemmas and that these patients are especially im...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Cortex
سال: 2018
ISSN: 0010-9452
DOI: 10.1016/j.cortex.2018.07.002